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The dramatic decline in smallpox fatalities in response to Jenner's vaccine can be traced in the chart, which shows the number of deaths due to smallpox as a share of all deaths in London from 1629 to 1902.
28 lis 2022 · The strength and longevity of smallpox vaccination campaigns globally, combined with current demographic heterogeneity, have shaped the epidemiological landscape today, revealing substantial geographical variation in orthopoxvirus susceptibility.
The case fatality rate increases as years from vaccination increase, from nearly 0 percent if vaccination occurred less than 10 years prior to contact to over 10 percent when vaccination occurred more than 20 years prior to contact.
21 gru 2020 · This study presents the complete historical weekly record of smallpox mortality in London over more than 250 years (1664-1930), describes it using spectral analyses, and discusses it in the context of events and interventions that might have influenced infectious disease dynamics.
30 mar 2023 · The studies suggested that smallpox is 80.7% efficacious to prevent human monkeypox and the immunity provided by prior smallpox vaccination is long-lasting. Moreover, the smallpox vaccination decreases the risk of human monkeypox by 5.2-folds.
Patients are most contagious after the rash appears. 1 The mortality rate for the most pathogenic variety of smallpox, variola major, was about 30%.
Number of reported smallpox cases by world region. Smallpox cases reported worldwide. Smallpox death rate versus life expectancy in Sweden. Smallpox deaths as a share of all deaths in London 1629 to 1902.
