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  1. Based on historical data, the death rate following smallpox vaccination is approximately one death per million persons receiving an initial dose and one death per four million among persons receiving another dose after the first dose .

  2. Before the introduction of a smallpox vaccine in 1796, around 7% of all deaths annually were caused by smallpox. Following the introduction of the vaccine, a clear decline in smallpox deaths is visible.

  3. Patients are most contagious after the rash appears. 1 The mortality rate for the most pathogenic variety of smallpox ... In addition to unacceptable side effects and problems related to production, although the vaccine is effective, it is unclear how long it provides protection. ... (CCSV) is a replication-competent vaccinia virus vaccine ...

  4. Deaths from smallpox are generally due to secondary infection of lesions, pneumonia, toxemia, and hypotension. Death rates in unvaccinated patients, particularly those with the more severe form of the disease, can be as high as 50 percent.

  5. Based on past experience, it is estimated that 1 to 2 people out of every 1 million people vaccinated could die as a result of life-threatening reactions to the vaccine. Other Serious Side Effects.

  6. 30 mar 2023 · There was a 20-fold increase in monkeypox incidence from the 1980s (0.72 per 10,000) to 2006–2007 (14.42 per 10,000) in rural DRC, 30 years after the cessation of smallpox vaccination. In 2005–2007, they identified 760 laboratory-confirmed human monkeypox cases.

  7. 11 sie 2003 · The Neff study reported 3 accidental infections from 517 vaccinations in the age group 1 to 4 years (CR, 5803 cases per million; 95% CI, 1198–16,863). For all age groups combined, there were no deaths among 857 cases of accidental infection (CFR, 0 deaths per 100 cases; 95% CI, 0.0–0.4).

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