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Zygosity refers to the genetic makeup of the pregnancy, or the number of zygotes that become fertilized leading to a multiple birth. Twins, in rarer cases triplets, quadruplets (four), quintuplets (five), arising from a single fertilized ovum are termed monozygotic (MZ).
1 sty 2020 · Zygosity is the term that describes the number of zygotes from which a multiple pregnancy is produced. In the simplest form, twins may either be monozygotic (i.e., produced from a single zygote) or polyzygotic, namely, dizygotic, trizygotic, etc. (i.e., produced from two, three or more zygotes).
7 sty 2021 · We applied two different approaches to call sequence variants, one for postzygotic mutations that are present in a subset of the cells and another optimized for germline mutations (described...
10 lip 2024 · This is supported by documented cases of human blastocysts containing two separate groups of ICMs in a single blastocoel (Meintjes et al. 2001; Mio and Maeda 2008; Noli et al. 2015), and even triple ICMs (Lee et al. 2008), leading to monochorionic twin or triplet pregnancies respectively.
10 gru 2011 · Monozygotic (MZ) twins originate when a single egg is fertilized to form one zygote, which then divides into two embryos. Although they share the same genotype they are not phenotypically identical.
2 dni temu · Identical twins (also called monozygotic twins) result from the fertilization of a single egg by a single sperm, with the fertilized egg then splitting into two. Identical twins share the same genomes and are nearly always the same sex.
13 sty 2021 · A new study in Nature Genetics used whole-genome sequencing of monozygotic twins, their parents, partners and offspring to identify and characterize early developmental mutations, as well as the...
