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13 sty 2021 · Looking at 381 monozygotic twin pairs and 2 triplets, the authors first estimated the number of postzygotic mutations present in one twin but not the other.
10 lip 2024 · Splitting of the inner cell mass within a blastocyst leads to monochorionic monozygotic twins; if one embryo splits into two blastocysts, dichorionic monozygotic twins develop.
10 gru 2011 · Monozygotic (MZ) twins originate when a single egg is fertilized to form one zygote, which then divides into two embryos. Although they share the same genotype they are not phenotypically identical.
7 sty 2021 · Two of the triplets shared 2 mutations at a VAF of 9–19% and 27–39%, whereas the third triplet did not (Fig. 7b). Furthermore, we found a single pre-PGCS mutation at a VAF of 39% in the...
27 lut 2009 · Common knowledge of over a century has it that monozygotic and dizygotic twinning events occur by unrelated mechanisms: monozygotic twinning ‘splits’ embryos, producing anomalously re-arranged embryogenic asymmetries; dizygotic twinning begins with independent ovulations yielding undisturbed parallel embryogeneses with no expectation of departur...
1 sty 2020 · If two genetically distinct populations of cells were formed before repulsion, another distinct cellular differentiation event would have to occur in at least one of the resultant cell populations at the same embryological state in order to produce monozygotic triplets.
1 lip 2014 · Zygosity is the one that reflects the type of conception, i.e., whether twins arise from one or two fertilized eggs (MZ or dizygotic (DZ), respectively), whereas chorionicity refers to the type of placentation.
