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  1. The chorionicity and amnionicity should be determined in the first trimester. The chorionicity is determined by examining the mem-brane thickness at the site of their insertion into the placenta; a T sign indicates monochorionicity, while a lambda (λ) sign is diagnostic of dichorionicity (Fig. 1).7–9.

  2. Zygosity refers to the genetic makeup of the pregnancy, or the number of zygotes that become fertilized leading to a multiple birth. Twins, in rarer cases triplets, quadruplets (four), quintuplets (five), arising from a single fertilized ovum are termed monozygotic (MZ).

  3. Monochorionic – the babies share a placenta and chorion, which means they are identical. The chorionicity of triplets. For triplet pregnancies there are more possible combinations: Trichorionic – each baby has a separate placenta and chorion.

  4. 16 lis 2016 · Clinicians should be aware that monochorionic/dichorionic triplet pregnancies have higher fetal loss rates than trichorionic triplet pregnancies and may be complicated by feto–fetal transfusion syndrome, sGR and TAPS. Grade of recommendation: C. Selective reduction should be discussed in all higher order pregnancies including triplets. [New 2016]

  5. 4 gru 2019 · The guideline recommends women with a triplet pregnancy (irrespective of chorionicity) should be offered a cesarean birth. The updated guideline also informs optimal fetal monitoring in labor when a vaginal birth is chosen for a twin pregnancy.

  6. 1 sty 2020 · Indeed, although they share a common genotype, monozygotic twin pairs almost invariably exhibit a variety of postzygotic genetic differences, ranging from different susceptibilities to disease to size differences.

  7. Twins or triplets can be identical (monozygotic) or non-identical (di/tri-zygotic). Identical twins or triplets have come from one egg, which has been fertilised by one sperm and has then split into two (or three) after fertilisation.

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