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Monoclonal B-cell lymphocytosis (MBL) is an asymptomatic condition in which individuals have increased blood levels of particular subtypes of monoclonal lymphocytes (i.e. an aberrant and potentially malignant group of lymphocytes produced by a single ancestral cell).
11 lis 2021 · The term monoclonal B-cell lymphocytosis (MBL) describes the presence of a clonal B cell population with a count of less than 5 × 109/L and no symptoms or signs of disease. Based on the B cell count, MBL is further classified into 2 distinct subtypes: ‘low-count’ and ‘high-count’ MBL.
19 lip 2023 · Monoclonal B-cell lymphocytosis is when your body produces an elevated number of identical B cells. In some cases, it can develop into chronic lymphocytic leukemia.
28 kwi 2023 · Monoclonal B-cell lymphocytosis (MBL) is a condition in which a person has an excessive amount of abnormal B cells, which are a type of white blood cell known as lymphocytes.
6 lip 2023 · Monoclonal B cell lymphocytosis (MBL) refers to a monoclonal population of B lymphocytes <5000 cells/microL (<5 x 10 9 /L) in peripheral blood for ≥3 months, without other features of a B cell lymphoproliferative disorder (eg, lymphadenopathy, organomegaly, cytopenias, or extramedullary involvement) [1,2].
7 lip 2015 · Monoclonal B lymphocytosis (MBL) is defined as the presence of a clonal B-cell population in the peripheral blood with fewer than 5 × 10 9 /L B-cells and no other signs of a lymphoproliferative disorder. The majority of cases of MBL have the immunophenotype of chronic lymphocytic leukemia (CLL).
Recent studies suggest that more than 4% of the general population over age 40 harbor a population of clonal B-cells with the phenotype of either CLL or another B-cell malignancy, a condition now designated monoclonal B-cell lymphocytosis (MBL).
