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Patients with a history of immunosuppression should be tested for progressive multifocal leukoencephalopathy by cerebrospinal fluid (CSF) examination for the presence of JC virus. A high index of suspicion should remain for neoplasia, including primary central nervous system (CNS) lymphoma and gliomatosis cerebri.
22 lis 2019 · Given the success in preventing stroke in general, with important reductions in incidence and mortality, are new treatments to target cSVD progression even necessary? That they are is supported by the evidence that many patients with cSVD experience progression with cognitive and functional decline despite conventional stroke risk reduction.
12 lip 2019 · These studies will also clarify the true variation in disease phenotype and prognosis. In analogy to adrenoleukodystrophy, 56 we foresee that milder and later-onset leukodystrophy variants than are now known will be identified more frequently, since these variants are currently underdiagnosed.
The life expectancy of a person with white matter disease depends on many factors, including the specific type, the rate at which it progresses, and the complications it causes. Research has ...
19 lip 2021 · The recent results of the minimally invasive surgery plus alteplase for intracerebral hemorrhage evacuation (MISTIE) III trial demonstrated the safety of the procedure and a reduction in mortality compared to medical treatment.
Our findings suggested that LCC could be diagnosed by clinical presentations, neuroimaging and gene detection, and biopsy might not be necessary. Therefore, we propose a diagnostic flow chart for neuroimaging in leukoencephalopathy, cerebral calcifications and cysts.
27 gru 2022 · A pooled analysis of 38 studies comprising 20,322 patients prescribed antithrombotics after ischemic stroke or transient ischemic attack (TIA) found rapidly increasing ICH risk with CMB burden, 75 and showed that a CMB-based model (MICON-ICH) outperformed existing bleeding risk models in ICH prediction. 76 However, CMBs were also associated ...
