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Patients with a history of immunosuppression should be tested for progressive multifocal leukoencephalopathy by cerebrospinal fluid (CSF) examination for the presence of JC virus. A high index of suspicion should remain for neoplasia, including primary central nervous system (CNS) lymphoma and gliomatosis cerebri.
30 sty 2024 · What to know about white matter disease. Prognosis and life expectancy. Symptoms. Causes. Types. Stages. Treatment. In children. Summary. White matter disease, or leukoaraiosis, means there is...
22 lis 2019 · Given the success in preventing stroke in general, with important reductions in incidence and mortality, are new treatments to target cSVD progression even necessary? That they are is supported by the evidence that many patients with cSVD experience progression with cognitive and functional decline despite conventional stroke risk reduction.
This retrospective study aims to describe the cellular changes (using immunohistochemical studies) in a spectrum of ischemic leukoencephalopathy. Methods: We studied 24 white matter ischemic injury cases with a well-documented interval from the ischemic event of interest.
23 kwi 2024 · Cerebral small vessel disease, also known as cerebral microangiopathy, is an umbrella term for lesions in the brain attributed to pathology of small arteries, arterioles, capillaries, venules, or small veins. It is the most common cause of vascular dementia/cognitive impairment and is a major cause of ischemic and hemorrhagic strokes.
White matter disease is a spectrum that can appear on MRI as mild to severe. Symptoms associated with it can range from nonexistent to severe. Because of this, the prognosis (outlook) for white matter disease varies from person to person.
Abstract. Purpose of Review: More than 100 heritable disorders can present with abnormal white matter on neuroimaging. While acquired disorders remain a more common cause of leukoencephalopathy in the adult than genetic causes, the clinician must remain aware of features that suggest a possible genetic etiology. Recent Findings:
