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Antibiotics that have been reported to be useful in cats include metronidazole (at 10 mg/kg bid for maximum 3 weeks) and amoxicillin (if concurrent biliary duct disease). Prednisolone is usually started at 1–3 mg/kg daily, and this dosage is to be tapered every 3–4 weeks once clinical response has been attained.
- How I Treat: Inflammatory Bowel Disease - WSAVA2013 - VIN
Metronidazole (Flagyl), an inhibitor of cell-mediated...
- How I Treat: Inflammatory Bowel Disease - WSAVA2013 - VIN
IBD patients with mild to moderate clinical disease activity and normal serum albumin concentrations are first treated sequentially with dietary and antibiotic trials. If they fail to respond to either of these trials, immunosuppressive therapy is initiated.
Metronidazole (Flagyl), an inhibitor of cell-mediated immunity, has been frequently used as an adjunctive agent for the management of IBD. The dose of metronidazole is 10–15 mg/kg q 12 hours. Metronidazole tablets have a sharp, unpleasant, metallic taste when scored that can cause severe salivation.
Medical Treatment Metronidazole may be recommended along with dietary modification as the first medical therapy. Metronidazole has antibiotic, anti-inflammatory, and antiprotozoal properties, and is usually fairly well tolerated, although some cats may lose their appetite when given this drug.
Genotoxicity in cats has been reported following a single dose of metronidazole at 20 mg/kg PO. 28. Tylosin. Anecdotally, tylosin (a macrolide antibiotic) has been used to treat IBD colitis in cats. Similar to metronidazole, its mechanism(s) of action may include antibacterial and immunomodulatory properties. Clinical evidence is relatively ...
28 lip 2020 · Corticosteroids are typically recommended in cats that do not respond to dietary therapy and metronidazole, or cats that present with signs of advanced disease (such as weight loss and/or hypoalbuminema).
Anecdotally, tylosin (a macrolide antibiotic) has been used to treat IBD colitis in cats. Similar to metronidazole, its mechanism(s) of action may include antibacterial and immunomodulatory properties. Clinical evidence is relatively sparse on the efficacy of this drug for treatment of feline IBD. Formulation → Oral (powder)
