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15 wrz 2020 · Survival has improved, but varies widely by GPA for patients with non–small-cell lung, breast, melanoma, GI, and renal cancer with brain metastases from 7-47 months, 3-36 months, 5-34 months, 3-17 months, and 4-35 months, respectively. Conclusion.
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PURPOSEConventional wisdom has rendered patients with brain...
- Journal of Clinical Oncology
Founded in 1964, the American Society of Clinical Oncology,...
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27 kwi 2018 · Melanoma brain metastasis is associated with an extremely poor prognosis, with a median overall survival of 4–5 months. Since 2011, the overall survival of patients with stage IV melanoma has been significantly improved with the advent of new targeted therapies and checkpoint inhibitors.
10 lis 2021 · Melanoma brain metastases (MBM) frequently exist at diagnosis or develop during the course of the disease. 1–3 Historically, median overall survival following diagnosis of brain metastases was 3–13 months. 4 Despite recent improvements in survival outcomes associated with the introduction of immune checkpoint inhibitors and targeted therapy ...
2 mar 2021 · Historically, melanoma brain metastases (MBM) have carried a poor survival prognosis of 4 to 6 months; however, the introduction of immunotherapy and targeted precision medicines has altered the survival curve for advanced melanoma.
One of the biggest problems faced by melanoma patients are brain metastases, which occur in up to 60% of patients with advanced melanoma, and the presence of brain metastases significantly worsens the prognosis of patients.
28 lut 2023 · Brain metastasis in cutaneous melanoma (CM) has historically been considered to be a dismal prognostic feature, although recent evidence has highlighted the intracranial activity of combined immunotherapy (IT).
21 cze 2020 · Malignant melanoma is the third most common type of tumor that causes brain metastases. Patients with cerebral involvement have a dismal prognosis and their treatment is an unmet medical need.
