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1. pmc.ncbi.nlm.nih.gov › articles › PMC8374436Pathophysiology of Major Depression by Clinical Stages

   pmc.ncbi.nlm.nih.gov › articles › PMC8374436

   The comprehension of the pathophysiology of the major depressive disorder (MDD) is essential to the strengthening of precision psychiatry. In order to determine the relationship between the pathophysiology of the MDD and its clinical progression, ...

2. www.ncbi.nlm.nih.gov › books › NBK559078Major Depressive Disorder - StatPearls - NCBI Bookshelf

   www.ncbi.nlm.nih.gov › books › NBK559078

   10 kwi 2023 · Major depressive disorder can be managed with various treatment modalities, including pharmacological, psychotherapeutic, interventional, and lifestyle modification. The initial treatment of MDD includes medications or/and psychotherapy.

3. www.nature.com › articles › s41392/024/01738-yMajor depressive disorder: hypothesis, mechanism, prevention and...

   www.nature.com › articles › s41392/024/01738-y

   9 lut 2024 · Major depressive disorder (MDD), a main cause of disability worldwide, is characterized by physical changes such as tiredness, weight loss, and appetite loss.

4. www.ncbi.nlm.nih.gov › books › NBK430847Depression - StatPearls - NCBI Bookshelf

   www.ncbi.nlm.nih.gov › books › NBK430847

   17 lip 2023 · Pathophysiology. The underlying pathophysiology of major depressive disorder has not been clearly defined. Current evidence points to a complex interaction between neurotransmitter availability and receptor regulation and sensitivity underlying the affective symptoms.

5. www.nature.com › articles › tp2015137Pathophysiology of major depressive disorder: mechanisms ... -...

   www.nature.com › articles › tp2015137

   29 wrz 2015 · Several biological mechanisms with a possible role in major depressive disorder (MDD)’s pathophysiology have been identified, and it has been hypothesized that these mechanisms may have a...

6. pubmed.ncbi.nlm.nih.gov › 34421705Pathophysiology of Major Depression by Clinical Stages

   pubmed.ncbi.nlm.nih.gov › 34421705

   5 sie 2021 · An increased severity of depressive symptoms and worse sleep quality were correlated with levels low of SC and CAR, and with high levels of mBDNF. These results point out a strong relationship between the stages clinical of MDD and changes in a range of relevant biological markers.

7. www.nature.com › articles › s41572/023/00454-1Major depressive disorder | Nature Reviews Disease Primers

   www.nature.com › articles › s41572/023/00454-1

   24 sie 2023 · Major depressive disorder (MDD) is characterized by persistent depressed mood, loss of interest or pleasure in previously enjoyable activities, recurrent thoughts of death, and physical and...