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Equianalgesic conversions used in this calculator are based on the American Pain Society guidelines and critical review papers regarding equianalgesic dosing. 4, 5, 6, 7 When possible, chronic-dosing studies have been used, including bidirectional and dose-dependent conversions.
Overview. Oral Morphine Equivalents (OME) are approximations of the equianalgesic effects of other opioids compared to oral morphine. Thus, OMEs indicate how much of the reference drug oral morphine would be required to treat pain as effectively as the opioid morphine is compared with.
Consider the need to adjust dose for conditions that increase opiate risk (eg elderly, co-morbidities, renal or hepatic impairment). Where dose equivalence is expressed as a range, use the value that produces the lowest equivalent dose and titrate as necessary.
This opioid dose equivalence table is intended for comparison of different opioid and opioid formulations in individual patients or in patient cohorts. Caution is required if opioid dose equivalence tables are used to guide opioid switching, as the administration of a calculated ‘equivalent’ dose of the replacement opioid may lead to overdosage.
Equianalgesic Doses of Opioid Analgesics*,†. † See also Kreutzwiser D, Tawfic QA and Pain Guidelines (based on Quill TE: Primer of Palliative Care, ed. 7. Chicago, Academy of Hospice and Palliative Medicine, 2019). OMME = oral morphine milligram equivalents.
29 lut 2024 · Add up all the scheduled and breakthrough opioid doses in 24 hours. Using the equianalgesic dose chart, determine the 24-hour OME of the current opioid. (24-hour OME = (24-hour dose of current opioid x [30 /Number of equianalgesic units for the current opioid])
If converting from IV to oral hydromorphone, use a conversion ratio of 1.5:4, ie. multiply IV dose by 3 to get equianalgesic IV dose. Calculating the equipotent dose: Example: Convert patient from morphine 30mg po q4h to hydromorphone IV. Step 1: Calculate current total daily usage of opioids.
