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Systemic Lupus Erythematosus. An inflammatory, multisystem, autoimmune disease of unknown etiology with protean clinical and laboratory manifestations and a variable course and prognosis. Lupus can be a mild disease, a severe and life-threatening illness, or anything in between.
El lupus eritematoso sistémico (LES) es una compleja enfermedad reumática multisistémica de ori-gen autoinmune con una morbimortalidad importantes. Es una de las enfermedades autoinmunes más comunes, con una prevalencia estimada de 20-150/100.000 habitantes.
Systemic lupus erythematosus (SLE) is a chronic systemic autoimmune disease of variable severity and course, characterised by a tendency for flare (figure 1).1 In SLE, both innate and adaptive immune responses are involved.
ABSTRACT. Research elucidating the pathogenesis of systemic lupus erythematosus (SLE) has defined two critical families of mediators, type I interferon (IFN- I) and autoantibodies targeting nucleic acids and nucleic acid- binding proteins, as fundamental contributors to the disease.
1 sty 2021 · PDF | On Jan 1, 2021, Sarah N. Al-Gahtani published A Review of Systemic Lupus Erythematosus (SLE): Symptoms, Risk Factors, Treatment, and Health Related Quality of Life Issues | Find, read...
Since 2008, when the first EULAR recommen-dations for the management of systemic lupus erythematosus (SLE) were published and widely adopted,1 a series of specific recommendations on disease monitoring, neuropsychiatric SLE and lupus nephritis (LN), pregnancy and women’s health issues in SLE have been developed.2–5 More recently, updated recomme...
Systemic lupus erythematosus (SLE) is a multisystemic autoimmune disease, characterised by the presence of autoantibodies towards nuclear antigens, immune complex deposition, and chronic inflammation at classic target organs, such as skin, joints, and kidneys.
