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13 mar 2019 · Lupus erythematosus panniculitis (LEP) is characterized by chronic and recurrent subcutaneous inflammatory lesions and is considered a form of chronic cutaneous lupus erythematosus (CLE). Clinically, LEP appears as erythematous, deeply indurated, tender plaques and nodules.
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5 cze 2023 · Lupus erythematosus panniculitis (LEP) is a type of lupus that causes painful lesions under the skin. Learn about its symptoms, causes, and treatment.
Lupus erythematosus panniculitis is rare and difficult to diagnose, particularly in those without SLE or DLE at presentation. Our findings, which demonstrate diagnostic delay and refractory disease, underscore the need for earlier diagnosis and treatment to prevent pain and irreversible atrophy.
11 mar 2019 · The first stage of lupus panniculitis is active inflammation with painful nodules, followed by the second stage of subcutaneous atrophy that can be cosmetically disfiguring. Lupus panniculitis, like systemic lupus erythematosus (SLE), occurs more commonly in women.
Early diagnosis and proper treatment is pivotal to improve the prognosis of such patients. INTRODUCTION. Lupus erythematosus panniculitis (LEP), also called lupus erythematosus profundus, is a rare variant of chronic cutaneous lupus erythematosus (CCLE). 1–4 LEP commonly presents in the third-to-sixth decades of life, with female predilection ...
Lupus panniculitis (LEP) is an uncommon subtype of chronic cutaneous lupus characterized by painful, indurated subcutaneous nodules, and/or depressed plaques distributed on the proximal extremities, breasts, buttocks, and face. Discoid lesions commonly overlie the area of panniculitis.
The best described forms of panniculitis occurring in the setting of connective tissue disease are lupus erythematosus panniculitis (LEP) and lupus profundus, panniculitis associated with dermatomyositis, and morphea and scleroderma associated panniculitis.