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7 maj 2024 · Treatment goals include reducing disease exacerbations, hospitalizations, and organ damage due to the disease or treatment toxicity. Hydroxychloroquine is standard of care for SLE and has been associated with a significant reduction in mortality.
Drug-induced lupus erythematosus (DILE) is best defined as an adverse reaction of treatment with a certain drug taken continuously over time, inducing lupus-like symptoms.
12 cze 2024 · Discussion. This cohort study showed that SGLT2i use was associated with a significantly lower risk of incident lupus nephritis, dialysis, kidney transplant, heart failure, and all-cause mortality compared with SGLT2i nonuse in patients with SLE and type 2 diabetes.
Despite these advances, infections remain a major cause of morbidity and mortality in patients with systemic lupus erythematosus (SLE) throughout the world. 1–3 Almost two decades ago, the Lupus Survival Study Group examined the causes of death of 1103 patients with SLE.
Systemic lupus erythematosus (SLE) is an autoimmune disease characterised by the loss of self-tolerance and formation of nuclear autoantigens and immune complexes resulting in inflammation of multiple organs.
25 paź 2020 · Infections are common in patients with SLE and are associated with high morbidity and mortality [5, 9]. This susceptibility may result partly from immunosuppressive treatment [51] and aberrations in the immune system associated with SLE, predisposing patients to infection [52].
