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1 lip 2021 · It is estimated that 70–85% of SLE patients develop cutaneous lesions during the course of the disease, and that cutaneous LE may be the first presenting sign in approximately 25% of these patients. 2, 3 Meanwhile, only a small subset (10–20%) of patients with cutaneous LE will eventually develop SLE, and the number varies between different ...
21 kwi 2024 · Lupus erythematosus (LE) is an autoimmune inflammatory disease with complex etiology. LE may present as a systemic disorder affecting multiple organs or be limited solely to the skin. Cutaneous LE (CLE) manifests with a wide range of skin lesions divided into acute, subacute and chronic subtypes.
16 cze 2023 · The various cutaneous manifestations of SLE are presented in detail separately. (See "Overview of cutaneous lupus erythematosus".) Many patients develop oral and/or nasal ulcers, which are usually painless in contrast to herpetic chancre blisters. Nasal ulcers may lead to nasal septal perforation.
19 maj 2021 · Cutaneous lupus can be subdivided into three main categories: acute cutaneous lupus erythematosus, subacute cutaneous lupus erythematosus, and chronic cutaneous lupus erythematosus. Physical exam, laboratory studies, and histopathology enable differentiation of cutaneous lupus subtypes.
Lupus erythematosus (LE) is an autoimmune inflammatory disease with a wide clinical spectrum from life-threatening multi-organ inflammation in systemic lupus erythematosus (SLE) to limited skin disease in cutaneous LE (CLE).
25 lip 2012 · This paper covers the SLE-specific cutaneous changes: malar rash, discoid rash, photosensitivity, and oral mucosal lesions as well as SLE nonspecific skin manifestations, their pathophysiology, and management. A deeper thorough understanding of the cutaneous manifestations of SLE is essential for diagnosis, prognosis, and efficient management.
The majority of patients with systemic lupus erythematosus (SLE) have cutaneous manifestations at some point in their disease course. The skin findings in SLE are classified as SLE-specific or SLE-nonspecific based on histopathologic findings.
