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  1. 26 paź 2022 · Acute cutaneous lupus erythematosus (ACLE) characterized by violaceous to erythematous patches and thin plaques involving the malar cheeks. Importantly, this pathognomonic “butterfly rash” of lupus strikingly spares the nasolabial folds helping to distinguish ACLE from disease mimics.

  2. 16 cze 2023 · The various cutaneous manifestations of SLE are presented in detail separately. (See "Overview of cutaneous lupus erythematosus".) Many patients develop oral and/or nasal ulcers, which are usually painless in contrast to herpetic chancre blisters. Nasal ulcers may lead to nasal septal perforation.

  3. 30 sie 2024 · Hematologic abnormalities are common in systemic lupus erythematosus (SLE), both at diagnosis and throughout the course of the disease. The major hematologic manifestations of SLE may include isolated or concurrent cytopenias (including anemia, leukopenia, and thrombocytopenia), lymphadenopathy, and/or splenomegaly.

  4. 22 sty 2022 · Skin lesions are present in more than 90% of lupus patients. Cutaneous manifestations can occur as part of SLE or as an isolated manifestation of disease confined to the skin, known as cutaneous lupus erythematosus (CLE).

  5. Cutaneous manifestations of SLE comprise four diagnostic criteria and multiple other clues to a potential diagnosis of lupus . The first is malar rash, which is characterized by an erythematous rash over the cheeks and nasal bridge.

  6. 19 maj 2021 · Cutaneous lupus erythematosus includes a wide array of visible skin manifestations and can progress to systemic lupus erythematosus in some cases. Cutaneous lupus can be subdivided into three main categories: acute cutaneous lupus erythematosus, subacute cutaneous lupus erythematosus, and chronic cutaneous lupus erythematosus.

  7. 5 gru 2020 · The three main categories of SLE-specific manifestations are acute cutaneous LE (acLE), encompassing the malar rash and a generalized maculopapular rash, subacute cutaneous LE (scLE), with its annular or psoriasiform eruptions, and various forms of chronic cutaneous LE .