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4 sie 2023 · Acute cutaneous lupus erythematosus (ACLE) may be localized or generalized. The hallmark ACLE lesion is the malar rash or the butterfly rash, an erythematous raised pruritic rash involving the cheeks and nasal bridge.
10 lis 2022 · ABSTRACT. The majority of patients with systemic lupus erythematosus (SLE) have cutaneous manifestations at some point in their disease course. The skin findings in SLE are classified as SLE-specific or SLE-nonspecific based on histopathologic findings.
9 sie 2019 · Cutaneous lupus erythematosus (CLE) is an autoimmune disease that can present as an isolated skin disease or as a manifestation within the spectrum of systemic lupus erythematosus. The...
30 sie 2024 · Hematologic abnormalities are common in systemic lupus erythematosus (SLE), both at diagnosis and throughout the course of the disease. The major hematologic manifestations of SLE may include isolated or concurrent cytopenias (including anemia, leukopenia, and thrombocytopenia), lymphadenopathy, and/or splenomegaly.
Serologic testing may reveal the presence of antibodies directed against double-stranded DNA (anti-dsDNA), Smith antigen (anti-Smith), U1 ribonucleoprotein (anti-U1RNP) and/or anti-Ro antibodies. In the vast majority of cases, the lupus band test, which is a DIF technique, is positive.
21 kwi 2024 · Lupus erythematosus (LE) is an autoimmune inflammatory disease with complex etiology. LE may present as a systemic disorder affecting multiple organs or be limited solely to the skin. Cutaneous...
19 maj 2021 · Acute cutaneous lupus erythematosus (ACLE), subacute cutaneous lupus (SCLE), and discoid lupus (DLE) are the three most common manifestations of cutaneous lupus erythematosus (CLE).
