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A recently published study by Feng et al (2014) demonstrated gender-specific differences in reference intervals of serum Lp-PLA 2 levels in 763 healthy Chinese Han subjects, with significantly lower serum levels in females compared to males (75th percentile: female 489 U/L (18-49 years) resp. 542 U/L (50-88 years), and males 579 U/L (18-87 years).
Lp-PLA 2, or lipoprotein-associated phospholipase-A 2, measures disease activity within the artery wall below the collagen or calcified cap due to the activation of macrophages. Lp-PLA 2 is not an acute phase reactant. When disease is active in the artery, increased levels of Lp-PLA 2 are produced by macrophages and
1 sty 2020 · The PLAC test is a blood test used to measure serum activity of lipoprotein-associated phospholipase A2 (Lp-PLA2), an enzyme that breaks down oxidized low-density lipoprotein in the...
20 gru 2021 · What do the results of the LP-PLA2 test convey? The normal range of LP-PLA2 in your blood is 200 nanograms per milliliter (ng/mL). A higher value indicates that you are an increased risk of CVD including coronary artery disease and stroke.
Lipoprotein-associated phospholipase A2 (Lp-PLA2), also known as platelet activating factor Acetylhydrolase, is an inflammatory enzyme that circulates bound mainly to low density lipoproteins and has been found to be localized and enriched in atherosclerotic plaques.
What is the PLAC® Test? The PLAC ® Test measures the amount of Lp-PLA 2 in the bloodstream. Lp-PLA 2 is an enzyme that can assess the amount of inflammation in your arteries due to a build-up of cholesterol. Why should I get the PLAC® Test? The PLAC® Test can help assess your risk for heart disease or stroke.
The normal range for Lp-PLA2 is less than 200 ng/mL. If your results are higher, you may have inflammation in your arteries. When both your CRP and your Lp-PLA2 are higher, you may be at greater risk of having a stroke.
