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15 wrz 2022 · A commonly accepted paradigm (based on Virchow’s triad of thrombogenesis) posits the pathogenesis of LV thrombus as occurring as a result of the interplay of 3 factors: (1) stasis attributable to reduced ventricular function, (2) endocardial injury, and (3) inflammation/hypercoagulability (Figure 1).
1 maj 2023 · The optimal management of left ventricular thrombus (LVT) remains controversial. Despite decreasing incidence with improvements in early percutaneous revascularization, LVT is estimated to occur after 6.3% of ST elevation myocardial infarctions.1 Because a key tenet of Virchow's triad for thrombosis includes blood stasis, nonischemic ...
23 wrz 2022 · On the basis of limited data, patients with nonischemic cardiomyopathy with LV thrombus should be treated with OAC for at least 3–6 months, with discontinuation if LV ejection fraction improves to >35% (assuming resolution of the LV thrombus) or if major bleeding occurs.
Abstract. Introduction Left ventricular thrombus (LVT) is a frequent complication of left ventricular systolic dysfunction (1). Incidence following acute myocardial infarction is estimated at 13–20% and up to 15% in with non-ischaemic cardiomyopathy (2, 3). Once diagnosed, guidelines recommend anticoagulation with vitamin K antagonists (VKA ...
Left ventricular (LV) thrombus is a feared complication of LV dysfunction associated with high rates of systemic embolism, morbidity, and mortality. Traditionally, LV thrombus has been associated with acute myocardial infarction (MI).
Management of LV thrombus (LVT) is challenging and crucial to prevent the potential development of thromboembolic complications such as stroke. Anticoagulation with warfarin is recommended for the prevention of thromboembolic events, but novel oral anticoagulants (NOAC) have been used in clinical practice without supporting evidence.
From the ESC Working Group on Thrombosis. Date. Title. 01/10/2024. Targeting Fibrinolytic Inhibition for Venous Thromboembolism Treatment: Overview of an Emerging Therapeutic Approach. 01/10/2024. Aspirin-free strategy for percutaneous coronary intervention in acute coronary syndrome based on the subtypes of acute coronary syndrome and high ...