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24 sie 2023 · Complete surgical resection is the standard treatment for localized GIST. The goal is an R0 surgery with complete removal of the tumor, including an intact pseudocapsule.
The size, location and stage of the GIST help determine the best way to remove it. We offer comprehensive surgical options for GIST removal, including: Laparoscopic surgery: This minimally invasive technique removes small tumors through tiny incisions, leading to easier recoveries.
20 mar 2021 · Surgery for metastatic GIST often requires multivisceral resection given its predilection for distant metastasis. All surgery should begin with a thorough examination of the abdomen for evidence of radiographically occult disease.
Surgery for Metastatic GIST. Frequently, gastrointestinal stromal tumor (GIST cancer) is already metastatic at the time of diagnosis. GIST metastases typically involve the liver and/or the peritoneum. In this case the surgeon may not be able to resect all visible tumors.
Liver transplantation for unresectable GIST liver metastases could be an option in the spectrum of therapeutic indications. Prospective randomised studies are necessary to provide the evidence needed.
1 paź 2019 · The gastrointestinal stromal tumor (GIST) is a digestive neoplasm of mesenchymal lineage. The treatment strategy for receptor tyrosine kinase-mutated GISTs is well defined. Wild-type GISTs (WT-GISTs) respond unsatisfactorily to specific kinase inhibitors. Moreover, evidence shows that repeat surgery has limited benefit.
Liver resection of potentially resectable metastases can improve the results of medical treatment. In cases of unresectability, the role of liver transplantation (LT) has not been well-studied. Materials and methods: A review of the literature was undertaken from January 1995 to December 2020 following the PRISMA and AMSTAR guidelines.
