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Langerhans cells (LCs) reside in the epidermis as a dense network of immune system sentinels. These cells determine the appropriate adaptive immune response (inflammation or tolerance) by interpreting the microenvironmental context in which they encounter foreign substances.
- Langerhans Cells—Revising Their Role in Skin Pathologies
(1) Langerhans cells (LCs) within the epidermis take up...
- Langerhans Cells: Sensing the Environment in Health and Disease
Langerhans cells make up 3–5% of all nucleated cells in the...
- Langerhans Cells-Programmed by the Epidermis - PubMed
Langerhans cells (LCs) reside in the epidermis as a dense...
- Langerhans Cells—Revising Their Role in Skin Pathologies
(1) Langerhans cells (LCs) within the epidermis take up antigen; (2) LCs internalize and process the antigen, and present the produced peptides on their surface via MHC molecules; (3) LCs migrate to the skin draining lymph nodes where they prime CD45RA + naïve T cells; (4) Activated T cells migrate to the skin, where they produce cytokines and ...
31 sty 2018 · Langerhans cells make up 3–5% of all nucleated cells in the epidermis and occupy the stratum spinosum, a suprabasal epidermal layer that is characterized by “spiny” keratinocytes that undergo reinforcement of their cytoskeleton.
Langerhans cells make up 3–5% of all nucleated cells in the epidermis and occupy the stratum spinosum, a suprabasal epidermal layer that is characterized by “spiny” keratinocytes that undergo reinforcement of their cytoskeleton.
Langerhans cells (LCs) are a specialized subset of dendritic cells (DCs) that populate the epidermal layer of the skin. Langerin is a lectin that serves as a valuable marker for LCs in mice...
19 wrz 2017 · Langerhans cells (LCs) are epidermis-resident antigen-presenting cells that share a common ontogeny with macrophages but function as dendritic cells (DCs). Their development, recruitment and...
29 lis 2017 · Langerhans cells (LCs) reside in the epidermis as a dense network of immune system sentinels. These cells determine the appropriate adaptive immune response (inflammation or tolerance) by interpreting the microenvironmental context in which they encounter foreign substances.
