Search results
Calculates total daily morphine milligram equivalents. There is no completely safe opioid dose, and this calculator does not substitute for clinical judgment. Use caution when prescribing opioids at any dosage, and prescribe the lowest effective dose.
In patients receiving long-acting opioid formulations (SR, transdermal), a "rescue" dose for breakthrough pain is recommended. 12 Generally, an immediate-release form of the same opioid is used (eg, morphine IR with morphine SR). The size of the breakthrough dose should be 5-15% of the patient's 24-hour baseline dose.
1mg – 2mg (1,3,4) Potency if switching from hydromorphone to morphine is less than from morphine to hydromorphone
Remember that a 100 MICROGRAM fentanyl patch is 0.1 MILLIGRAMS of fentanyl PER HOUR. Convert each number in your list to IV morphine equivalents, by using column 2. For example, if the bioavailable codeine dose is 100 mg, the IV morphine equivalent is 10mg.
As the total daily chronic dose of morphine increases, the equianalgesic dose ratio (morphine:methadone) changes (American Pain Society 2016). Total daily dose should be divided by 3; delivered every 8 hours.
When morphine at lower doses (e.g., 30–60 mg/d orally) is switched to methadone, the potency may be 3 to 5 times; when switched from high doses (e.g., >300 mg/d orally), the potency may be 12 times or even higher.
14 sie 2023 · Less than 6 months (not mechanically ventilated): Initial dose: 0.025 to 0.03 mg/kg IV or 0.075 to 0.09 mg/kg orally every 4 to 6 hours as needed to manage pain 6 months or older; weight less than 45 kg: 0.1 mg/kg IV or 0.3 mg/kg orally every 4 to 6 hours as needed to manage pain 6 months or older; weight 45 kg or more:
