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Thus, choosing a single value of 1.5 mL/min/kg to declare a dog as renal-impaired will be too low for small dogs (giving some false negative results) and too high for giant dogs (some false positive results). Breed may also affect the reference intervals.
Determination of glomerular filtration rate (GFR) is considered crucial in the evaluation of companion animal (cat, dog) renal disease, because the GFR directly relates to the functional renal mass.
Results of both tests should be interpreted in light of patient’s hydration status. Urine specific gravity. UPC >0.5 in dogs; UPC >0.4 in cats. 0.6 0.7 1.0. Sept ’15 Oct ’15 Nov ’15. Urine protein to creatinine (UPC) ratio. <1.030. 1.030. 1.035. See www.iris-kidney.com for more detailed staging, therapeutic, and management guidelines.
2 sie 2019 · Glomerular filtration rate estimation results from individual dogs in Groups A1, A2, and B were interpreted using categories of: GFR Group 1: GFR increased or <20% decreased from the mean GFR of the body weight category, kidney disease considered excluded or unlikely as a cause of presenting clinical signs; GFR Group 2: ≥20% but <30% decrease ...
Blood creatinine concentration is the most commonly used marker of glomerular filtration rate (GFR) in dogs and cats. Creatinine is produced from the non-enzymatic degradation of creatine and creatine phosphate in skeletal muscle and therefore serum creatinine concentrations reflect the patient's muscle mass as well as GFR.
FIGURE 1. Curvilinear inverse relationship between serum creatinine (sCr) and glomerular filtration rate (GFR). Note that, on the right side of the graph, relatively large reductions in GFR result in only minor changes in sCr, while the opposite relationship is demonstrated at the top of the graph.
Dog kidney problems? Understand more with our dog kidney failure stages chart and get info on how to help your dog feel better.
