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An analytical method to measure 2,3,7,8-tetrachlorodibenzo-p-dioxin and other 2,3,7,8-tetrachlorodibenzo-p-dioxin isomers in human serum which uses a highly specific cleanup procedure and high-resolution gas chromatography/high resolution mass spectometry was described.
In animals, 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD, “dioxin”) causes various systemic effects at a wide range of exposure concentrations, including tumorigenesis, immunological dysfunction, and teratogenesis.
2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) is a polychlorinated dibenzo-p-dioxin (sometimes shortened, though inaccurately, to simply 'dioxin') [3] with the chemical formula C 12 H 4 Cl 4 O 2. Pure TCDD is a colorless solid with no distinguishable odor at room temperature.
2,3,7,8-tetrachlorodibenzodioxin (TCDD) is the most toxic of the family of 210 compounds. Seventeen of these PCDD/F compounds having chlorines in the 2,3,7, and 8 positions are designated for special concern because their shape makes them particularly bioactive.
21 gru 2021 · 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) is known to be a human carcinogen based on sufficient evidence of carcinogenicity from studies in humans, both epidemiological and on the mechanism of carcinogenesis.
9 wrz 2020 · 2,3,7,8-Tetrachlorodibenzo- p -dioxin (TCDD), a persistent environmental contaminant, induces steatosis that can progress to steatohepatitis with fibrosis, pathologies that parallel...
6 mar 2009 · 2,3,7,8-Tetrachlorodibenzo-p-dioxin is the most toxic of 75 chlorinated dibenzo-p-dioxin (CDD) congeners. CDDs are a class of manufactured chemicals that consist of dioxin skeletel structures with chlorine substituents.
