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I think you might be topped off on thiamine and getting past the daily recommended might be causing you issues. I read that the totally body content of thiamine is about 25-30 mg, and the body is quite good at absorbing a decent amount of supplemental thiamine hcl in one sitting..
Other sources have suggested that intestinal barrier dysfunction could be in part caused by thiamine deficiency; high-dose supplementation may help epithelial cell metabolism return to normal, in turn improving digestive symptoms for those who have fatigue associated with some form of IBS.
Yes and yes. When you have the MTHFR gene mutation you're advised to take the methylated forms, but these forms can unfortunately still lead to symptoms and people who undermethylate suddenly start to overmethylate on them, which can lead to symptoms. So changes in methylation cause issues for some. It's complicated.
15 sty 2024 · This lesser-known B vitamin is important for keeping your body, brain and heart healthy. Learn more about the benefits of thiamine — and how much you need.
7 kwi 2023 · Functions & Benefits of Thiamine. 1) Metabolism. The body needs Vitamin B1 to make ATP, the body’s main energy-carrying molecule. Thiamine helps in the conversion of carbohydrates into glucose, which is the preferred source of energy that the body runs off of to keep your metabolism running smoothly. It also helps break down proteins and fats [3].
1 wrz 2024 · Thiamine (vitamin B1) is a water-soluble vitamin that helps the growth and function of your body's cells. It's needed for a healthy liver, skin, eyes, hair, and brain. It's also thought to help strengthen your immune system.
Started 25mg TTFD thiamine up to 75mg daily. Think it's suppose to be more absorbable and get through the blood brain barrier if I remember correctly. My ME/CFS doc said I could try up to 100mg.
