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Some years later, a role for thiamine deficiency in diabetic neuropathy became evident, and some pilot studies evaluated the putative effects of thiamine supplementation. However, the administration of thiamine and its lipophilic derivative benfotiamine for the treatment of this complication gained consensus only at the end of the '90 s.
- PMC8505293
Genetic defects in intracellular thiamine transport are...
- PMC8505293
Thiamine comes as tablets containing 50mg or 100mg of thiamine. It also comes as slow-release tablets containing 100mg of thiamine and as a liquid containing 100mg in 5ml. Your dose depends on why you need thiamine and whether it's been prescribed by a doctor.
8 maj 2020 · High-dose thiamine therapy may have a therapeutic effect on early-stage diabetic nephropathy [18]. Thiamine therapy is also suggested to be useful in preventing renal and cardiovascular events in people with type II DM, thereby increasing the quality of life and reducing further complications [19].
5 cze 2021 · One-month thiamine administration decreased glycemia and leptin concentrations in subjects with type 2 diabetes [37], and improvements were described in glucose tolerance [38] and blood pressure [39] in subjects with hyperglycaemia, following high-dose thiamine supplementation.
1 wrz 2024 · Diabetes: Studies suggest people with diabetes may have lower thiamine levels in the body. For people with diabetes who start to develop kidney damage ( nephropathy ), thiamine supplementation might be recommended.
31 gru 2019 · Interpretation: Thiamine supplementation does not affect glycaemic outcomes, however reduces triglycerides while increasing HDL. Multicentre well-designed RCT with higher doses of thiamine and a follow-up period of 1–2 years will provide better evidence. PROSPERO registration number CRD42020170520.
High-dose thiamine supplementation may prevent or slow the progression of hyperglycemia toward diabetes mellitus in individuals with impaired glucose regulation.
