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  1. 23 wrz 2016 · Spice is not a single drug, but a range of laboratory-made chemicals that mimic the effects of tetrahydrocannabinol (THC), the main psychoactive component of cannabis.

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  2. There are five major categories for synthetic cannabinoids: classical cannabinoids, non-classical cannabinoids, hybrid cannabinoids, aminoalkylindoles, and eicosanoids. Classical cannabinoids are analogs of THC that are based on a dibenzopyran ring.

  3. 25 wrz 2016 · Spice is not a single drug, but a range of laboratory-made chemicals that mimic the effects of tetrahydrocannabinol (THC), the main psychoactive component of cannabis. Research suggests that Spice and other forms of synthetic cannabis is capable of producing much more intense and prolonged effects at much lower doses than natural cannabis.

  4. 14 maj 2024 · Synthetic cannabinoids are lab-made drugs. Spice is a nickname for a substance containing one or more synthetic cannabinoids. Synthetic cannabinoids were originally designed to mimic the effects of cannabis. However, they are more harmful and unpredictable than cannabis.

  5. Like THC, they bind to the same cannabinoid receptors in the brain and other organs as the endogenous ligand anandamide. More correctly designated as cannabinoid receptor agonists, they were initially developed over the past 40 years as therapeutic agents, often for the treatment of pain.

  6. 26 wrz 2016 · Spice is not a single drug, but a range of laboratory-made chemicals that mimic the effects of tetrahydrocannabinol (THC), the main psychoactive component of cannabis. Research suggests that Spice and other forms of synthetic cannabis is capable of producing much more intense and prolonged effects at much lower doses than natural cannabis.

  7. Unlike THC, the synthetic cannabinoids present in Spice are high-potency, high-efficacy, cannabinoid-receptor full agonists. Since standard urine toxicology does not test for the synthetic cannabinoids in Spice, it is often used by those who want to avoid detection of drug use.