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6 cze 2022 · Iron homeostasis is mainly controlled by intestinal absorption because iron does not have active excretory mechanisms for humans. Thus, efficient intestinal iron bioavailability is essential to reduce the risk of iron deficiency anemia. There are two forms of iron, heme and nonheme, found in foods.
- PMC Free Article
Iron metabolism. Iron is a trace element that is required...
- Ferfer
Micronization and microencapsulation of iron into liposomes,...
- Comparison Study of Iron Bioaccessibility From Dietary Supplements and Microencapsulated Preparations
In the form of lactate, one tablet of dietary supplements...
- A Review
Iron absorption generally starts from the first part of the...
- Impact of Ascorbic Acid on The In Vitro Iron Bioavailability of a Casein-Based Iron Fortificant
Interestingly, a similar enhancement (i.e., by 1.18-fold p <...
- Biochemical and Nutritional Characteristics of Buffalo Meat and Potential Implications on Human Health for a Personalized Nutrition
The human consumption of food animal products is the main...
- PubMed
Based on the Institute of Medicine's review of the...
- PMC Free Article
4 sie 2017 · Systemic iron homeostasis–from intestinal iron uptake to iron utilization, recycling, and storage–can be largely understood by considering how iron is handled by four main cell types: enterocytes, erythrocyte precursors, macrophages, and hepatocytes.
8 sie 2014 · Absorption of dietary iron by the proximal intestine is thus accurately regulated by cellular and systemic factors to ensure that overall body iron levels are maintained at adequate levels. Iron balance is controlled in part by the liver-derived, serum-borne, peptide hormone hepcidin (HEPC), which functions to block intestinal iron absorption ...
11 sty 2001 · Intestinal mucosal cells in the duodenum and upper jejunum absorb the iron. The iron is coupled to transferrin (Tf) in the circulation which delivers it to the cells of the body. Phytates, tannins and antacids block iron absorption.
27 lis 2002 · While the intestine is the site of net iron absorption into the body, most iron entering plasma results from iron recycled from senescent or damaged red blood cells. Transcription of ferroportin is iron regulated, but again the mechanism of regulation is unknown.
6 sty 2011 · The intracellular step of iron absorption refers to the intracellular distribution of the newly transported iron to the basolateral surface, to the mitochondria (e.g., biosynthesis of heme and iron-sulfur cluster), or to iron binding proteins (e.g., non-heme iron binding proteins and ferritin).
24 lis 2011 · The formation of red blood cells requires about 30 mg of iron daily and this is balanced by an equal flux of iron from the breakdown of senescent red blood cells by the reticuloendothelial (RE) cells in the spleen, liver (Kupffer cells), and bone marrow.
