Search results
11 lis 2024 · For some people with abnormal thyroid glands, excessive iodine can trigger or worsen hypothyroidism. While initially, you may have more energy, high doses can cause an "iodine crash" that leaves you feeling exhausted and achy within a few days.
Thyroid avidity and the trapping of iodine are upregulated in iodine deficiency and suppressed in cases of overexposure. Iodine deficiency results in the inadequate production of T4. In response to decreased blood T4 levels, the pituitary gland increases TSH to restore the circulating levels of T4.
Abstract. Severe iodine deficiency causes hypothyroidism that results in impaired somatic growth and motor development in children. Mild and moderate iodine deficiencies cause multifocal autonomous growth of thyroid, which results in thyrotoxicosis.
12 sty 2015 · In mild-to-moderate iodine deficiency, the thyroid gland is able to compensate for deficient dietary intake by increasing thyroid activity, which maintains thyroid hormone production, but at a price: in some individuals, chronic stimulation of the thyroid leads to thyroid nodularity and autonomy.
Iodide itself, however, plays an important role in regulating the activity of the thyroid gland (termed autoregulation). Excess iodine given to a person with normal thyroid gland activity leads to an initial reduction in organification and hormone synthesis and secretion, the Wolff-Chaikoff effect.
24 kwi 2024 · For some people, iodine or iodine-containing products may worsen autoimmune thyroid problems such as Hashimoto’s and Graves’ disease, and cause enlargement of the thyroid (goitre). 21 On the other hand, some healthcare professionals believe that a high iodine intake, such as seen in Japanese women, can largely prevent breast cancer. 2
Iodide absorption in the gastrointestinal tract is mediated by the sodium-iodide symporter (NIS), which also mediates the uptake of iodide into the thyroid follicular cell (see Figure 1) [7,8]. Iodide is rapidly cleared from the circulation by the thyroid gland and kidneys.
