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Background: Observations by pharmacists monitoring anticoagulated patients suggested that patients with diabetes often require more frequent international normalized ratio (INR) monitoring than patients without diabetes. The purpose of this investigation was to examine the association between glycemic control and therapeutic anticoagulation ...
To examine the association of the INR with mortality we calculated hazard ratios (95% confidence intervals) per 1-SD increase in INR using the Cox proportional hazards model adjusted for age and gender (model 1) or additionally adjusted for BMI, LDL-C, HDL-C, diabetes mellitus, hypertension, smoking and the use of antiplatelet or lipid lowering ...
28 sty 2019 · Indeed, when patients were stratified by quartile of international normalized ratio (INR) values out of range, presence of diabetes was independently associated with worst INR control in warfarin-treated AF patients .
30 lip 2009 · Its variable dose response and narrow therapeutic index mandate periodic monitoring of the international normalized ratio (INR). 1 Target INR ranges of 2.0 to 3.0 or 2.5 to 3.5 have been recommended for most indications because INR values in these ranges are associated with the best combination of thrombosis reduction and bleeding avoidance. 1 ...
1 wrz 2015 · Presently, the most commonly used summary measure of international normalized ratio (INR) control for research and quality assurance is percent time in therapeutic range (TTR). 5 – 11,14 In particular, we are referring to individual TTR, which is more tightly linked to outcomes than center-level TTR, as we have shown. 15 In addition to TTR ...
1 maj 2023 · International normalized ratio (INR) is the preferred test of choice for patients taking vitamin K antagonists (VKA). It can also be used to assess the risk of bleeding or the coagulation status of the patients. Patients taking oral anticoagulants are required to monitor INR to adjust the VKA doses because these vary between patients.
How to use the INR to determine the dose of warfarin and monitor its anticoagulant effect. In the pages that follow we offer some practical tips on the art and science of using warfarin safely and effectively.
