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1 mar 2021 · We propose a framework to help organize and understand these microgravity effects on the human brain: Spaceflight Perturbation Adaptation Coupled with Dysfunction (SPACeD). We consider instructive parallels between patterns of brain effects associated with spaceflight and observations in human aging neuroscience.
Research over the past decade has demonstrated two co-occurring patterns of spaceflight effects on the brain and behavior: dysfunction and adaptive plasticity. Evidence indicates the spaceflight environment induces adverse effects on the brain, including intracranial fluid shifts, gray matter changes, and white matter declines.
Gravity also affects the flow of blood through the brain; at accelerations beyond 5g, this begins to affect the brain’s electrical activity, producing patterns that resemble epileptic seizures.
16 sty 2017 · Gravity has a profound effect on fluid distribution and pressure within the human circulation. In contrast to prevailing theory, we observed that microgravity reduces central venous and intracranial pressure.
Understanding the effects of increased and decreased gravity on central nervous system is essential for developing proper physical and cognitive countermeasures to assure safe and effective space missions and human survival in space.
2 cze 2019 · Most important, understanding the influences of gravity on CSF homeostasis and brain health may provide insights into abnormalities of CSF homeostasis such as idiopathic normal pressure hydrocephalus.
1 mar 2021 · Based on the evidence available to date, we propose that spaceflight effects on the brain represent both adaptations as well as impairments. The altered sensory inputs of microgravity provide a unique environment for inducing adaptive plasticity in the central nervous system.
