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30 lip 2024 · Inhibiting IL-11 in mice extends lifespan and reduces aging signs, with potential implications for human aging treatments. Researchers from the Medical Research Council Laboratory of Medical Science and Imperial College London have discovered that ‘switching off’ a protein called IL-11 can increa
18 lip 2024 · Anti-IL-11 therapy boosted metabolism, with the animals producing calorie-burning brown fat, not problematic stores of white fat, blocked the loss of muscle mass and strength, and protected...
24 lip 2024 · A protein called interleukin 11 (IL-11) appears to play a crucial role in aging, with scientists extending the lifespans of mice by up to 25 percent simply by blocking the molecule's effects. Could it work in humans?
17 lip 2024 · Abstract. For healthspan and lifespan, ERK, AMPK and mTORC1 represent critical pathways and inflammation is a centrally important hallmark 1, 2, 3, 4, 5, 6, 7. Here we examined whether IL-11, a...
18 lip 2024 · FULL STORY. Scientists at the Medical Research Council Laboratory of Medical Science and Imperial College London have discovered that 'switching off' a protein called IL-11 can significantly...
17 lip 2024 · Blocking an inflammatory molecule known as interleukin-11 (IL-11) extends the lifespan of mice, suggesting that drugs inhibiting IL-11 may have anti-ageing effects in people, too.
16 cze 2023 · Preclinical studies indicate that 9MW3811 can strongly bind to IL-11 and block the activation of its downstream signaling pathways, which is expected to prevent fibrosis.
