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17 lip 2024 · Here we examined whether IL-11, a pro-inflammatory cytokine of the IL-6 family, has a negative effect on age-associated disease and lifespan.
24 lip 2024 · A study in Nature in July 2024[1], raised the idea that blocking the interleukin 11 (IL-11) by using an IL-11 antibody could be a proposition for a healthy increase in lifespan, based on the outcomes in their experimental mouse subjects.
24 lip 2024 · A protein called interleukin 11 (IL-11) appears to play a crucial role in aging, with scientists extending the lifespans of mice by up to 25 percent simply by blocking the molecule's effects.
17 lip 2024 · Blocking an inflammatory molecule known as interleukin-11 (IL-11) extends the lifespan of mice, suggesting that drugs inhibiting IL-11 may have anti-ageing effects in people, too.
18 lip 2024 · Anti-IL-11 therapy boosted metabolism, with the animals producing calorie-burning brown fat, not problematic stores of white fat, blocked the loss of muscle mass and strength, and protected...
16 cze 2023 · Preclinical studies indicate that 9MW3811 can strongly bind to IL-11 and block the activation of its downstream signaling pathways, which is expected to prevent fibrosis.
Abstract. Omega-3 polyunsaturated fatty acids (n-3 PUFAs) exert a negative effect on IL-6 production in several liver disorders, including cirrhosis, acute liver failure and fatty liver disease. However, its effect on the production of IL-11, another important IL-6 family cytokine, remains unclear.
