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  1. 22 lip 2024 · Scientists have discovered that deactivating a protein called IL-11 can extend the healthy lifespan of mice by nearly 25%, raising the potential for similar benefits in humans.

  2. 18 lip 2024 · Anti-IL-11 therapy boosted metabolism, with the animals producing calorie-burning brown fat, not problematic stores of white fat, blocked the loss of muscle mass and strength, and protected...

  3. 17 lip 2024 · Double blocking was achieved with (1) H 2 O 2 for 10 min and (2) 2.5% normal horse serum for 1 h (S-2012, Vector Labs). vWAT sections were incubated overnight at 4 °C with primary antibody...

  4. 24 lip 2024 · A protein called interleukin 11 (IL-11) appears to play a crucial role in aging, with scientists extending the lifespans of mice by up to 25 percent simply by blocking the molecule's effects.

  5. 24 lip 2024 · A study in Nature in July 2024 [1], raised the idea that blocking the interleukin 11 (IL-11) by using an IL-11 antibody could be a proposition for a healthy increase in lifespan, based on the outcomes in their experimental mouse subjects.

  6. Abstract. Omega-3 polyunsaturated fatty acids (n-3 PUFAs) exert a negative effect on IL-6 production in several liver disorders, including cirrhosis, acute liver failure and fatty liver disease. However, its effect on the production of IL-11, another important IL-6 family cytokine, remains unclear.

  7. 17 lip 2024 · Scientists at the Medical Research Council Laboratory of Medical Science and Imperial College London have discovered that 'switching off' a protein called IL-11 can significantly increase the...

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