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1. scitechdaily.com › breakthrough-in-anti-aging-il-11-deactivation-boosts-lifespanBreakthrough in Anti-Aging: IL-11 Deactivation Boosts ... -...

   scitechdaily.com › breakthrough-in-anti-aging-il-11-deactivation-boosts-lifespan

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   30 lip 2024 · Inhibiting IL-11 in mice extends lifespan and reduces aging signs, with potential implications for human aging treatments. Researchers from the Medical Research Council Laboratory of Medical Science and Imperial College London have discovered that ‘switching off’ a protein called IL-11 can increase the healthy lifespan of mice by nearly 25%.

2. immunityageing.biomedcentral.com › articles › 10Inhibiting IL11: a novel approach to turning back the clock

   immunityageing.biomedcentral.com › articles › 10

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   21 paź 2024 · Studies have shown that IL-11 inhibition can lead to improved health span and lifespan in animal models, with potential applications in humans. By targeting IL-11, researchers aim to mitigate age-related diseases, such as cancer, fibrosis, and multimorbidity, which pose significant healthcare challenges worldwide.

3. www.nature.com › articles › s41580/024/00793-1IL-11 as a master regulator of ageing - Nature

   www.nature.com › articles › s41580/024/00793-1

   16 paź 2024 · Furthermore, the authors found that IL-11 inhibition has potent anti-ageing effects in both male and female mice, which suggests that it is a master regulator of senescence and ageing.

4. newatlas.com › medical › anti-aging-interleukin-11Anti-aging drug extends life up to 25%, staves off frailty and...

   newatlas.com › medical › anti-aging-interleukin-11

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   18 lip 2024 · Anti-IL-11 therapy boosted metabolism, with the animals producing calorie-burning brown fat, not problematic stores of white fat, blocked the loss of muscle mass and strength, and protected...

5. scitechdaily.com › revolutionary-anti-aging-therapy-could-extend-lifespan-by-25Revolutionary Anti-Aging Therapy Could Extend Lifespan by 25%

   scitechdaily.com › revolutionary-anti-aging-therapy-could-extend-lifespan-by-25

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   23 wrz 2024 · Researchers at Duke-NUS Medical School have discovered that interleukin-11 (IL11) plays a crucial role in the aging process, associated with higher levels of fat accumulation and muscle loss—key indicators of aging. Inhibiting IL11’s effects may enhance a healthy lifespan.

6. medicalxpress.com › news › 2024-07-scientists-interleukin-key-driver-agingScientists identify interleukin-11 as key driver of aging -...

   medicalxpress.com › news › 2024-07-scientists-interleukin-key-driver-aging

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   17 lip 2024 · Anti-IL-11 therapy counteracts effects of aging. After establishing IL-11's role in aging, the team demonstrated that by applying anti-IL-11 therapy in the same preclinical model,...

7. medicine.net › Scientists-identify-interleukin-11-as-key-driver-of-agingScientists identify interleukin-11 as key driver of aging

   medicine.net › Scientists-identify-interleukin-11-as-key-driver-of-aging

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   7 sie 2024 · The team demonstrated in preclinical models that the protein interleukin-11 (IL-11) actively promotes aging and that giving an anti-IL-11 therapy not only counteracts the deleterious effects of aging but also increases lifespan.