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While HPV infection can cause cervical cancer in women, it is also a strong risk factor for HIV acquisition. This may have a biological basis; HPV infection induces genital inflammation, vaginal barrier disruption, and influx of activated target T cells, which have all been implicated in HIV risk.
HPV infection and HIV acquisition in women. Averbach[], Low[] and Smith-McCune[] et al increased risk of HIV acquisition associated with infection with any HPV genotype compared to no HPV infection in women.The point estimate from all three were consistent with a harmful effect of HPV infection (aHR=1.71, aHR=2.40 and aHR=2.26 respectively) although the association was only statistically ...
HIV-related immunodeficiency has complex effects on female genital HPV, which include increased risks of infection, multiple types, persistence, reactivation and the risk to develop pre-invasive and invasive disease.
5 cze 2018 · If reducing HPV provides benefits for HIV, this would optimize HPV programmes, particularly in the context of combination prevention, providing additional incentives for programme implementation. Our comprehensive review can help inform decisions on HPV vaccination in women and men, including MSM.
19 lis 2019 · Here we study associations between HPV and HIV acquisition and relate these to vaginal cytokine profiles in an observational cohort of women at high risk of HIV infection (CAPRISA 004, n =...
These results provide evidence for synergistic HIV and HPV interactions of clinical and public health relevance. HPV vaccination may directly benefit PLHIV, and help control both HPV and HIV at the population level in high prevalence settings.
HIV-positive women have higher human papillomavirus (HPV) prevalence and cervical cancer (CC) incidence than HIV-negative women, partly due to HIV’s modifying effect on HPV pathogenesis. We synthesized the literature on the impact of HIV on HPV natural history.
