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HPV infection and HIV acquisition in women. Averbach[], Low[] and Smith-McCune[] et al increased risk of HIV acquisition associated with infection with any HPV genotype compared to no HPV infection in women.The point estimate from all three were consistent with a harmful effect of HPV infection (aHR=1.71, aHR=2.40 and aHR=2.26 respectively) although the association was only statistically ...
While HPV infection can cause cervical cancer in women, it is also a strong risk factor for HIV acquisition. This may have a biological basis; HPV infection induces genital inflammation, vaginal barrier disruption, and influx of activated target T cells, which have all been implicated in HIV risk.
HIV-related immunodeficiency has complex effects on female genital HPV, which include increased risks of infection, multiple types, persistence, reactivation and the risk to develop pre-invasive and invasive disease.
16 lis 2020 · HIV enhances human papillomavirus (HPV)-induced carcinogenesis. However, the contribution of HIV to cervical cancer burden at a population level has not been quantified. We aimed to investigate cervical cancer risk among women living with HIV and to estimate the global cervical cancer burden associated with HIV. Methods.
One woman with cervical cancer died in a car accident before any treatment was started. The second woman diagnosed with cervical cancer was successfully operated on and received radiotherapy and chemotherapy as per the recommended treatment guidelines.
27 mar 2018 · Objective: HIV-positive women have higher human papillomavirus (HPV) prevalence and cervical cancer incidence than HIV-negative women, partly because of HIV's modifying effect on HPV pathogenesis. We synthesized the literature on the impact of HIV on HPV natural history.
These results provide evidence for synergistic HIV and HPV interactions of clinical and public health relevance. HPV vaccination may directly benefit PLHIV, and help control both HPV and HIV at the population level in high prevalence settings.
