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Averbach [24], Low [25] and Smith-McCune [26] et al increased risk of HIV acquisition associated with infection with any HPV genotype compared to no HPV infection in women. The point estimate from all three were consistent with a harmful effect of HPV infection (aHR=1.71, aHR=2.40 and aHR=2.26 respectively) although the association was only ...
- HPV and the Risk of HIV Acquisition in Women - PMC
While HPV infection can cause cervical cancer in women, it...
- HPV and the Risk of HIV Acquisition in Women - PMC
5 cze 2018 · The main associations of interest were the relative risk (RR) of acquiring a new HPV infection or clearing an existing HPV infection (outcomes) by HIV serostatus (exposure) (review 1), and the RR of acquiring HIV infection (outcome) by HPV status (either prevalent, recent/incident or recently cleared HPV infection) (exposure) (review 2).
While HPV infection can cause cervical cancer in women, it is also a strong risk factor for HIV acquisition. This may have a biological basis; HPV infection induces genital inflammation, vaginal barrier disruption, and influx of activated target T cells, which have all been implicated in HIV risk.
HIV-related immunodeficiency has complex effects on female genital HPV, which include increased risks of infection, multiple types, persistence, reactivation and the risk to develop pre-invasive and invasive disease.
16 lis 2020 · We show that women living with HIV have a six-fold higher risk of developing cervical cancer compared with women without HIV infection. In view of this increased risk, we estimate that nearly 5% of all cervical cancer cases worldwide are attributable to HIV infection.
Human Papilloma Virus (HPV) is the most common sexually transmitted infection.1 HPV types 16 and 18 are responsible for nearly 50% of high grade cervical pre-cancers.2 Most HPV infections clear on their own, but persistent infection with these HPV types can cause cervical cancer.
19 lis 2019 · Considering the relationship between genital cytokines and HIV risk, these data highlight the importance of including HPV status in risk scoring profiles and emphasizes the benefit...
