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26 sie 2019 · The therapeutic dose of lithium is dangerously close to a toxic dose, and that year one of his patients — “W.B.”, a man with a 30-year history of bipolar disorder — appeared in the coroner ...
24 maj 2023 · In 1970, the US Food and Drug Administration approved lithium for the treatment of patients with bipolar disorder (BD). Today, lithium remains the gold standard for the management of BD in both acute and chronic cases.
24 kwi 2023 · Some of the lithium we rely on in the rechargeable batteries in our smartphones, laptops and electric vehicles was created during the Big Bang 13.8 billion years ago. The lithium cycle on Earth starts with lithium-bearing magma rising to the Earth’s crust during periods of volcanic activity, where.
20 maj 2016 · The modern history of lithium started in 1949 with John Cade’s contribution after he noted its specific effect in patients with mania (Cade 1949). In the late 1940s, Australian psychiatrist Cade sought a treatment for “psychotic excitement” (manic-depressive illness).
Lithium (from Ancient Greek λίθος (líthos) 'stone') is a chemical element; it has symbol Li and atomic number 3. It is a soft, silvery-white alkali metal. Under standard conditions, it is the least dense metal and the least dense solid element.
26 lis 2016 · The use of lithium was eventually approved by the US Food and Drug Administration (FDA) in 1970–1972, and it is now considered to be the gold standard for maintenance therapy and, in particular, the prevention of depression and mania in bipolar disorder.
Cade and Andrews traced the effect to the lithium ion itself, and after Cade ingested lithium himself to ensure its safety in humans, he proposed lithium salts as tranquilizers. He soon succeeded in controlling mania in chronically hospitalized patients with them.
