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  1. Misoprostol, a synthetic prostaglandin E1 analogue was used to induce labour artificially because of the safety concerns for pups and bitches. Misoprostol was successfully used in human subjects at the dose rate of 50 μg orally or 25 μg intravaginally.

  2. The beneficial effects on cervical ripening may make misoprostol a desirable agent for helping cervical dilatation on non pregnant women also. A few studies are available on the use of misoprostol as cervical priming agent before gynaecological procedures on non pregnant women.

  3. In dogs, treatment time can be reduced (usually by 48 hours) by the concurrent administration of prostaglandin E (misoprostol) intravaginally at 1–3 mcg/kg/day. The adverse effects of prostaglandins at this dosage (panting, trembling, nausea, and diarrhea) are mild and transient.

  4. Misoprostol For Dogs and Cats: Uses, Side Effects and Dose Calculator Based on Weight, Dose (mg/kg) and Concentration.

  5. Prior to biopsy, the veterinarian will conduct a physical examination of the prostate gland in addition to other diagnostic tests. There are a few approaches to prostatic biopsy. These include fine needle aspiration, ultrasound-guided needle biopsy, and excisional biopsy.

  6. How do I use misoprostol? Misoprostol tablets can be used either in the vagina, or under the tongue (sublingual). You and your doctor will discuss the best option for you. Using misoprostol in the vagina Misoprostol tablets should be placed deep into the vagina two hours before your planned admission time. 1. Go to the toilet and empty your ...

  7. In our study, we used 400 μg single dose of misoprostol by vaginal route 6 h prior to the procedures as a cervical priming agent. Our aim was to see the effectiveness of misoprostol by this approach. Though diagnostic hysteroscopy could be done using 4 mm scope without anesthesia in many cases.

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