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  1. This perspective presents a historical account of the discovery of the wonder drug, describes the biological nature of penicillin, and considers lessons that can be learned from the golden era...

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  2. In this review, we summarize the historic evolution of the knowledge about penicillin and cephalosporin, from the first observations on producer microorganisms and the chemistry of these antibiotics up to the modern ways of genetic engineering fo-cused on developing superproducer strains at an industrial level.

  3. This perspective presents a historical account of the discovery of the wonder drug, describes the biological nature of penicillin, and considers lessons that can be learned from the golden era of antibiotic research, which took place between the 1940s and 1960s.

  4. 1 paź 2019 · The first antibiotic, salvarsan, was deployed in 1910. In just over 100 years antibiotics have drastically changed modern medicine and extended the average human lifespan by 23 years. The discovery of penicillin in 1928 started the golden age of natural product antibiotic discovery that peaked in the mid-1950s.

  5. 1 lut 2022 · In the Philippines, a lower–middle income country in southeast Asia, cultural misconceptions and inadequate regulation and enforcement of antibiotic use have shaped provider and patient attitudes and behaviour.

  6. 6 lip 2015 · Penicillium chrysogenum has been used to produce the penicillin G as a secondary metabolite of P. chrysogenum, which has been used as a narrow spectrum penicillin antibiotic against...

  7. 23 paź 2021 · Following an accidental discovery of the mould, later identified as Penicillium rubens, as the source of the antibacterial principle (1928) and the production of a pure compound (1942),...

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