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  1. 14 lip 2022 · This primer discusses the use of high-sensitivity cardiac troponin (hs-cTn) testing in context of the 2021 multisociety guidelines for the evaluation and diagnosis of acute chest pain, with a notable focus on analytical aspects of the hs-cTn assays and their implications.

  2. High sensitivity troponin test is more sensitive, & more precise at low concentrations, than standard troponin. High-sensitivity troponin testing allows for faster MI “rule outs” in chest pain patients presenting to the ED. This leads to more efficient ED throughput.

  3. make important recommendations that include the recognition of high-sensitivity cardiac troponin (hs-cTn) as the preferred biomarker, endorsement of 99th percentile upper reference limits to define myocardial injury, and the use of clinical decision

  4. 22 lis 2011 · These levels used to be considered indicative of myocardial necrosis. However, with high-sensitivity troponin assays, circulating cTnT or cTnI can be found in the plasma as a result of transient ischemic or inflammatory myocardial injury.

  5. Hs-TnI assays allows for more accurate and precise troponin results at very low levels, which permits for the use of an accelerated chest pain algorithm for rapid rule-out/rule-in of AMI. The new hs-TnI reporting protocol will involve reporting results in ng/L (compared to the previous μg/L).

  6. 1 lip 2022 · Analytical considerations in deriving 99 th percentile upper reference limits for high-sensitivity cardiac troponin assays: educational recommendations from the IFCC committee on clinical application of cardiac bio-markers [published online June 18, 2022].

  7. 28 mar 2022 · High-sensitivity troponin assays are used to detect troponins, but at a much lower concentration than classical assays. These assays offer several advantages, first of all being the fact that they are highly sensitive, thus providing faster recognition of AMI (rule-in/rule-out).

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