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10 cze 2020 · Hepatitis E virus (HEV) generally causes self-limiting viral hepatitis. However, in pregnant women, HEV infection can be severe and has been associated with up to 30% mortality in the third trimester.
Verbal autopsies by trained physicians identified hepatitis, hepatic failure, or jaundice as the primary cause of death in 19 (7.8%) of 245 pregnancy-related deaths and 61 (7.2%) of 846 nonpregnant deaths recorded.
Hepatitis E infection during pregnancy, especially in the third trimester, is characterized by a more severe infection that sometimes results in fulminant hepatitis, increasing maternal and fetal mortality and morbidity.
20 lip 2023 · WHO estimates that hepatitis E caused approximately 44 000 deaths in 2015 (accounting for 3.3% of the mortality due to viral hepatitis). The virus is transmitted via the fecal-oral route, principally via contaminated water.
Hepatitis E virus (HEV) is a major cause of illness and of death in the developing world and disproportionate cause of deaths among pregnant women. Although HEV vaccine trials, including trials conducted in populations in southern Asia, have shown candidate vaccines to be effective and well-tolerate ….
10 cze 2020 · Background: Hepatitis E virus (HEV) generally causes self-limiting viral hepatitis. However, in pregnant women, HEV infection can be severe and has been associated with up to 30% mortality in the third trimester. Additionally, HEV infection in pregnancy is also associated with high rates of preterm labor and vertical transmission.
26 cze 2017 · HEV-1 and -2, endemic in African and Asian countries, can cause severe disease and fulminant hepatitis particularly in pregnant women, with up to 21% mortality [7]. In Europe, where HEV-3 is endemic, the infection is not associated with severe disease in pregnant women and thus they are not considered as risk group [8].
