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19 sie 2024 · Manuka honey significantly reduced tumor growth in mice with ER-positive breast cancer cells by 84% without affecting normal breast cells or causing major side effects. Higher concentrations of Manuka honey led to a greater reduction in cancer cell growth.
Manuka honey exerts its apoptotic effect on cancer cells through the induction of the caspase 9 which in turn activates the caspase-3, the executor protein. Apoptosis induced by Manuka also involves induction of DNA fragmentation, activation of PARP, and loss of Bcl-2 expression [ 31 ].
In addition to its wound healing, anti-microbial and antioxidant properties, several lines of evidence have highlighted the efficiency of honey and associated bioactive constituents as anti-tumor agents against a range of cancer types. Mechanistically, honey was shown to inhibit cancer cell growth through its pro-apoptotic, anti-proliferative ...
25 wrz 2024 · So, the results show that manuka honey, which is effective at concentrations as low as 0.6% (w / v) at 24 h, has a strong anti-proliferative effect on all cancer cell lines in a time- and dose-dependent manner. 3.2. The Anti-Proliferative Properties of Honey. Over the course of life, epithelial cells divide.
23 maj 2023 · Small clinical studies suggest potential benefits of manuka honey preparations for wound healing , atopic dermatitis , gingivitis , oral hygiene , rhinosinusitis , corneal edema , and dry eye symptoms .
19 sie 2024 · Summary: A new study found that Manuka honey could potentially be an alternative, natural option for breast cancer prevention and treatment -- particularly for estrogen receptor (ER)-positive...
27 sie 2024 · A new study suggests that Manuka honey may have health benefits as a ‘nutraceutical’ after achieving an 84% tumor growth reduction in mice with ER-positive breast cancer.
