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6 paź 2020 · Entry can be impacted by the presence of post-translational modification of receptors, including glycosylation (step 1). Upon entry, HMPV replication organelles can traffic along...
29 wrz 2023 · Understanding key time-to-event periods for each emerging variant of concern is critical as it can provide insights into the future trajectory of the virus and help inform outbreak preparedness and response planning.
The diagram indicates the ORFs of the early (E) and late (L) genes, the long control region (LCR), the two major promoters that drive viral expression (P97 and P742) and the two polyadenylation sites (A
28 paź 2020 · Despite sporadic zoonotic transmissions to humans upon prolonged contact and the limited human-to-human transmission, MERS-CoV infections are still detected 190.
6 lut 2021 · The variant, which is highly transmissible, was initially identified in the south of England in September 2020, and has since spread to dozens of countries around the world. It carries 17 mutations in its genome, including eight in the spike protein, which forms the basis of the three COVID-19 vaccines that have been licensed in the UK.
1 gru 2021 · There are many reasons for the paucity of robust empirical evidence on transmission of SARS-CoV-2 and the effectiveness of mitigation measures. It is extremely difficult to measure infectious SARS-CoV-2 virus in real world contexts, especially when airborne.
Moreover, epidemics caused by viruses such as severe acute respiratory syndrome coronavirus (SARS-CoV) and the newly emerging SARS-CoV-2 occur during the winter months. The mechanisms underlying the seasonal nature of respiratory viral infections have been examined and debated for many years.
