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  1. Melanin-index significantly decreased after 6 months of the intake (0.025 +/- 0.005 at the start vs 0.019 +/- 0.004 at 6 months) (p < 0.01), and also decreased at the end of study (0.021 +/- 0.005) (p < 0.05). GSE is effective in reducing the hyperpigmentation of women with chloasma.

  2. 9 sie 2024 · Explore the potential of grape seed extract in treating melasma with this comprehensive guide. From understanding its properties to scientific evidence, benefits, application methods, and precautions, this article covers everything you need to know about using grape seed extract for melasma.

  3. 26 lip 2024 · Explore the potential of grapefruit seed extract and grape seed extract in treating melasma. Learn how they work, scientific studies, benefits, drawbacks, and alternatives. Plus, precautions and recommendations for use.

  4. 16 lip 2024 · This article delves into the antioxidant properties of grape seed extract, its effects on skin health, and scientific studies that link it to melasma improvement. Learn how it may help, weigh the benefits and risks, and discover alternative treatments for this common skin condition.

  5. Grape seed extract. Grape seed extract contains proanthocyanidin, which is a powerful antioxidant. Although, there are no studies on the topical use of grape seed extract, but oral intake for 6 months has been found beneficial in patients with melasma in a study conducted by Yamakoshi, et al.

  6. 30 wrz 2019 · In conclusion this review article demonstrated that the grape seed extract exerts a potential health benefits against numerous diseases specifically cardiovascular disorders and wound healing effect.

  7. Yamakoshi et al. demonstrated the skin-lightening property of proanthocyanidin-rich grape seed extract in the treatment of melasma on Japanese women. Thus, most of these agents are used as over-the-counter adjuncts without much credible scientific evidence.

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