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An alanine transaminase (ALT) blood test measures the amount of ALT in your blood. ALT levels in your blood can increase when your liver is damaged, so healthcare providers often use an ALT blood test to help assess the health of your liver.
The alanine aminotransferase (ALT) test is a blood test that checks for liver damage. ALT used to be called serum glutamic-pyruvic transaminase (SGPT). So, it's sometimes called an SGPT...
Levels of ALT and AST are usually high in conditions such as hepatitis – possibly twenty to fifty times higher than normal. The ALT ‘value’, or level, is more specific to the liver than the AST value because the AST value may also be high if there is muscle damage elsewhere in the body.
27 lut 2024 · This review focuses on the significance of ALT in assessing hepatic injury and malfunction. ALT is aggregated primarily in the cytosol of hepatocytes, consists of 496 amino acids, and has a half-life of approximately 47 hours. ALT is detectable in serum at low concentrations (typically <30 IU/L).
22 sty 2024 · As a result, measuring AST levels through blood tests can be a valuable tool to assess liver function and identify potential liver concerns. ALT is an enzyme primarily found in the liver, with lesser amounts in the kidneys, heart, and muscles.
1 maj 2024 · Normal blood ALT and AST levels range from 0 to 40 IU/L. Abnormal results Marked elevations of ALT or AST (greater than 1,000 IU/L) suggest drug-induced liver injury (such as paracetamol overdose), acute viral hepatitis, ischaemic, or autoimmune hepatitis and may require referral to secondary care for further follow up.
Measuring ALT levels is the best way to test for liver damage. Some conditions that can cause elevations in ALT are hepatitis (liver inflammation), nonalcoholic fatty liver disease, heart failure, cancer and the effects of some drugs such as large doses of paracetamol.
