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14 lut 2020 · Fluorine labelling represents one promising approach to study proteins in their native environment due to efficient suppressing of background signals. Here, we systematically probe inherent...
12 lip 2021 · Excessive fluoride intake is associated with damage to the tissues and cells due to the inhibition of few metabolic enzymes and causes pro and antioxidant imbalance. Fluorosis causes ROS, RNS and is the most prevalent cause of oxidative damage of phospholipids in the plasma membrane.
1 gru 2020 · Fluoride causes alterations in the thyroid cells, e.g. mitochondrial swelling and disintegration, damage RNA and DNA and subsequently impede their repair processes, suppress glycolysis and endocrine functions in follicular cell.
9 mar 2020 · Exposure to high concentrations of fluoride, such as in a laboratory setting often exceeding 100 ppm, results in a wide array of toxicity phenotypes. This includes oxidative stress, organelle damage, and apoptosis in single cells, and skeletal and soft tissue damage in multicellular organisms.
The cell wall is a rigid structure that surrounds cells in plants, algae and fungi. It’s made mainly of the carbohydrate cellulose in plant and algae cells. In fungi, the cell wall is made of chitin. Its primary function is to support cells and prevent them from changing shape.
17 kwi 2015 · Fluoride is widely used as an anticariogenic agent but excessive ingestion may lead to systemic toxicity. Its biological effects are dependent on the amount, time of exposure and the metabolic handling of ingested fluoride.
Unique Properties of Fluorine and Their Relevance to Medicinal Chemistry and Chemical Biology. Takashi Yamazaki , Takeo Taguchi , and Iwao Ojima. 1.1 Fluorine - Substituent Effects on the Chemical, Physical and Pharmacological Properties of Biologically Active Compounds. The natural abundance of fl uorine as fl uorite, fl uoroapatite, ...
