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  1. 1 gru 2020 · At the cellular level, fluoride induces mitochondrial damage by modulating cytochrome C release and activating caspase-mediated apoptosis, consequently modifying membrane potential and mitochondrial membrane permeability and depleting energy stored in the form of ATP.

  2. 12 lip 2021 · Excessive fluoride intake is associated with damage to the tissues and cells due to the inhibition of few metabolic enzymes and causes pro and antioxidant imbalance. Fluorosis causes ROS, RNS and is the most prevalent cause of oxidative damage of phospholipids in the plasma membrane.

  3. 9 mar 2020 · A DNA microarray of a resistant strain of A. ferrooxidans offered one of the most complete pictures of fluoride tolerance, showing a change in expression of genes related to metabolism, protein synthesis, and cell membrane maintenance (Ma et al. 2016).

  4. Ingested fluoride forms hydrofluoric acid in the stomach. In this form, fluoride crosses cell membranes and then binds with calcium and interferes with various enzymes. Fluoride is excreted through urine. Fluoride exposure limits are based on urine testing, which is used to determine the human body's capacity for ridding itself of fluoride. [69 ...

  5. 1 sty 2011 · Gaseous fluoride enters the leaf through stomata and then dissolves in the water that permeates the cell walls. The natural flow of water in a leaf is toward the sites of greatest evaporation, which are the leaf margins and tips.

  6. 26 maj 2022 · Fluorine is a natural element present in water, food, soil, and air. However, due to being extremely electronegative, it largely emerges as fluoride (F − ), the monatomic anion of fluorine. Despite being present in only trace amounts in the body (∼2.6 g), fluoride has a significant nutritional and public health impact due to its role in the ...

  7. 8 mar 2022 · Fluorine is a natural element present in water, food, soil, and air. However, due to being extremely electronegative, it largely emerges as fluoride (F − ), the monatomic anion of fluorine. Despite being present in only trace amounts in the body (∼2.6 g), fluoride has a significant nutritional and public health impact due to its role in the ...